一个多电极阵列平台用于模拟,使用人类多能干细胞衍生的脑组合物

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Updated: Jul 6, 2026

Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue
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Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue

Published on: October 26, 2014

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Tong Pan1, Daniel C Jaklic1, Shivanshi Vaid1

  • 1Division of Pediatric Neurology, Department of Pediatrics, Michigan Medicine, Ann Arbor; Michigan Neuroscience Institute, University of Michigan, Ann Arbor.

Journal of visualized experiments : JoVE
|October 14, 2024
PubMed
概括

我们开发了一种方法,在两个月内记录人类大脑组合体的电活动. 这种新的测定方法可以长期研究神经网络发育和药物查.

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EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...