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通过臭氧化水对三种不同类型的禽流感病毒进行比较的无活化

Nader Maher Sobhy^1,2, Angie Quiñonez Muñoz¹, Christiana Rezk Bottros Youssef³

¹Veterinary Population Medicine Department and Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108.

|October 14, 2024

概括

臭氧化水 (O3W) 在三分钟内有效地使各种类型的禽流感病毒 (AIV) 亚型失活. 接触时间的延长并没有增强不活化,这表明臭氧

科学领域:

兽医病毒学兽医病毒学
传染病控制和控制传染病
环境微生物学环境微生物学

背景情况:

禽流感病毒 (AIV) 对家禽健康构成重大威胁,造成了相当大的经济损失.
通过受污染的菌体间接传播是AIV传播的主要途径.
有效的消毒策略对于控制AIV疫情至关重要.

研究的目的:

评估臭氧化水 (O3W) 在禁用三种AIV亚型 (H4N8,H4N6,H9N9) 的疗效.
为了评估七种不同的fomite材料的AIV无活化.
为了确定O3W对AIV的消毒的最佳接触时间.

主要方法:

曝光AIV亚型的fomites (纸板,牛仔,聚烯,发泡,不钢,玻璃和塑料) 的臭氧化水.
在接触时间3分钟和10分钟后的病毒减少量化.
对不同AIV亚型和矿材料的无活化率的分析.

主要成果:

在3分钟内,O3W在所有fomites上显示了所有测试的AIV亚型的显著失活.
艾滋病毒H9N9在特定菌体上显示>99%的减少;H4N8显示>97%的减少.
H4N6是最不敏感的,在3分钟后在纸板和聚烯上失活了98%.

结论:

臭氧化水是一种强大的消毒剂,可以在菌上对禽流感病毒进行防治.
3分钟的暴露足以产生大量的AIV失活,更长的时间没有额外的益处.
需要进行进一步的研究,以解决残留病毒无活化问题,并防止向幼鸟传播.

关键词:

禽流感病毒是禽流感病毒的一种病毒.福米特斯 (Fomites) 是一种植物.臭氧化水的臭氧化水.

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