时间生成模型用于学习生态瞬间评估数据的异质群体动态
Soohyun Kim1, Young-Geun Kim1,2, Yuanjia Wang1,2
1Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, 10032, United States.
Biometrics
|October 14, 2024
概括
精准精神病学旨在个性化精神障碍的表征. 一个新的异质动态受限博尔兹曼机器 (HDRBM) 模拟了复杂的生态瞬间评估数据,通过考虑群体动态和共变量来提高准确性和可解释性.
科学领域:
- 计算精神病学是一种计算精神病学.
- 机器学习用于医疗保健
- 精神病学数据科学是精神病学数据科学.
背景情况:
- 精准精神病学寻求使用动态过程来个性化精神障碍的表征.
- 通过移动技术进行的生态瞬间评估 (EMA) 产生了高频,多维,相关和层次的数据.
- 现有的模型,如混合效应模型和标准RTRBM,在处理EMA数据复杂性和异质性方面存在局限性.
研究的目的:
- 介绍一种新的时间生成模型,即异质动态受限博尔兹曼机器 (HDRBM).
- 解决现有模型的局限性,以捕捉使用共变量的群体内的异质群体动态.
- 为了证明HDRBM在模拟和现实世界EMA数据集上的有效性.
主要方法:
- 开发HDRBM,一种时间生成模型,结合共变量来学习异质群体动态.
- 在模拟和现实世界的生态瞬间评估数据集上应用和评估HDRBM.
- 将HDRBM性能与时间,层次数据的现有建模方法进行比较.
主要成果:
- 与现有方法相比,HDRBM显著提高了EMA数据建模的准确性和可解释性.
- 将共同变量纳入HDRBM框架允许探索参与者群体动态的潜在驱动因素.
- HDRBM有效地作为复杂的EMA研究的生成模型.
结论:
- 在精密精神病学中,HDRBM提供了一种强大的新方法来分析复杂,异质的EMA数据.
- 这种模型增强了我们理解心理健康研究中的个人和群体动态的能力.
- 通过利用共变量信息,HDRBM促进了对精神障碍的更准确和更可解释的洞察.
相关概念视频
00:56Noncompartmental Analysis: Statistical Moment Theory
92
Noncompartmental analyses leverage statistical moment theory to examine time-related changes in macroscopic events, encapsulating the collective outcomes stemming from the constituent elements in play. Statistical moment theory is a mathematical approach used to describe the time course of drug concentration in the body without assuming a specific compartmental model. SMT provides insights into drug absorption, distribution, metabolism, and elimination by treating drug concentration versus time...
92
02:30Naturalistic Observations
15.4K
If you want to understand how behavior occurs, one of the best ways to gain information is to simply observe the behavior in its natural context. However, people might change their behavior in unexpected ways if they know they are being observed. How do researchers obtain accurate information when people tend to hide their natural behavior? As an example, imagine that your professor asks everyone in your class to raise their hand if they always wash their hands after using the restroom. Chances...
15.4K
01:23Mechanistic Models: Compartment Models in Individual and Population Analysis
31
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
31
01:12Observational Learning
145
Albert Bandura's observational learning, also known as imitation or modeling, occurs when a person observes and imitates another's behavior. It is a quicker process than operant conditioning. A well-known example is the Bobo doll study, where children who saw an adult acting aggressively towards the doll were more likely to act aggressively when left alone, compared to those who observed a nonaggressive adult. Many psychologists view observational learning as a form of latent learning...
145
02:16Stereotype Content Model
14.0K
The Stereotype Content Model (SCM) was first proposed by Susan Fiske and her colleagues (Fiske, Cuddy, Glick & Xu, 2002; see also Fiske, 2012 and Fiske, 2017). The SCM specifies that when someone encounters a new group, they will stereotype them based on two metrics: warmth—or that group’s perceived intent, and how likely they are to provide help or inflict harm—and competence—or their ability to carry out that objective. Depending on the warmth-competence...
14.0K
01:23Behavioral Genetics and Its Designs
331
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
331