光生物调制治疗对植入物稳定性的影响:系统性审查和元分析
Mahnaz Arshad1,2, Yekta Mazidi3, Nasim Chiniforush4
1Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Photochemistry and photobiology
|October 14, 2024
概括
光生物调制疗法 (PBM) 增强了牙植入物的稳定性,特别是在早期的愈合阶段. 这一发现支持PBM作为改善植入物结果的有益治疗方法.
科学领域:
- 生物医学工程 生物医学工程
- 牙科植入物学 牙科植入物学
- 照相医疗 (photomedicine) 是一种医学技术.
背景情况:
- 牙植入物稳定性对于成功的骨整合至关重要.
- 光生物调节疗法 (PBM) 是一种使用光来刺激细胞过程的非侵入性治疗方法.
- 在提高牙植入物稳定性方面,PBM的有效性需要进一步研究.
研究的目的:
- 系统地评估光生物调制治疗对牙植入物稳定性的影响.
- 进行对随机对照试验 (RCT) 和对照临床试验 (CCT) 的元分析,调查PBM对植入物稳定性的影响.
主要方法:
- 在主要数据库 (PubMed,Cochrane,Embase,Scopus,Google Scholar) 进行了全面的系统文献搜索,截至2024年6月.
- 包括RCT和CCT专注于PBM对人类牙植入物稳定性的唯一影响.
- 关于植入物稳定性 (ISQ,PTV) 和样本大小的数据被提取用于元分析,使用Stata 17软件与随机效应模型.
主要成果:
- 17篇文章符合系统审查的条件,其中14篇被纳入了元分析.
- 在PBM组与对照组相比,在第2周 (ISQ) 和第4周和第8周 (PTV) 观察到植入物稳定性的统计学显著改善.
- 用I2统计来评估异质性,并应用随机效应模型进行分析.
结论:
- 光生物调制疗法对牙植入物稳定性产生有益影响.
- 在骨整合的早期阶段,PBM特别有效.
- 需要进一步的研究来探索最佳的PBM参数和长期结果.
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