用于深层组织生物成像和治疗的X射线/γ射线/超声波激活持久发光
1The Key Lab of Health Chemistry & Molecular Diagnosis of Suzhou, College of Chemistry, Chemical Engineering & Materials Science, Soochow University, Suzhou 215123, China.
ACS applied materials & interfaces
|October 14, 2024
概括
通过X射线,马射线或超声波激活的持久发光光体 (PLPs) 可提供深层组织生物成像和治疗. 这些材料克服了紫外线/可见光激活的局限性,用于增强的医疗应用.
科学领域:
- 材料科学 材料科学 材料科学
- 生物医学工程 生物医学工程
- 放射学 放射学是一门学科.
背景情况:
- 持久发光 (PLPs) 在生物成像和治疗中具有优势,因为它避免了自发光,并允许持续的治疗效果.
- 通过紫外线/可见光激活的传统PLP在体内应用有限,特别是在深层组织中.
研究的目的:
- 审查通过X射线,马射线和超声波激活的无机和有机PLP.
- 讨论这些新型PLP在深层组织生物成像和治疗中的生物医学应用.
- 引导PLP在深层组织中的可再生持久发光的设计.
主要方法:
- 对最近开发的通过穿透辐射 (X射线,马射线) 和超声波激活的无机和有机PLPs的文献综述.
- 分析表明持续发光的研究和生物医学应用.
主要成果:
- 各种无机和有机PLP可以通过X射线,玛射线和超声波来激活.
- 这些PLP显示出对成像和治疗深层瘤的前景.
- 在深层组织生物成像和治疗方面已经取得了成功的应用.
结论:
- 激活X射线/马射线/超声波的PLP代表了生物医学应用的重大进步.
- 这些材料可以实现持续的治疗活动,并改善深层组织的成像.
- 这些PLP的进一步开发可以增强光热学,生物感知和能量收获.
相关概念视频
Photoluminescence: Applications
380
Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
380
X-ray Imaging
5.4K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
5.4K
Photoluminescence: Fluorescence and Phosphorescence
1.6K
Photoluminescence is a process where a molecule absorbs light energy and re-emits it in the form of light. This phenomenon occurs when a substance absorbs photons, promoting its electrons to higher energy level excited states, followed by a relaxation process in which the electrons return to their original ground state energy levels and emit light. Photoluminescence is widely observed in various materials, including semiconductors, and organic and inorganic compounds.
A pair of electrons in a...
A pair of electrons in a...
1.6K
Imaging Studies II: Positron Emission Tomography and Scintigraphy
91
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
91
Positron Emission Tomography
4.0K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.0K


