墨西哥严重COVID-19患者的急性损伤和死亡率:病例控制研究
Ivette Mata-Maqueda1,2, Juan C Solís-Sáinz2, Guadalupe Zaldivar-Lelo de Larrea2
1Health Services of the State of Queretaro.
Cirugia y cirujanos
|October 14, 2024
概括
急性损伤 (AKI) 显著增加了严重疾病的冠状病毒疾病2019 (COVID-19) 患者的死亡风险. 早期功能查对于管理这些高风险个体至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
背景情况:
- 危急的冠状病毒疾病2019 (COVID-19) 对患者的生存构成重大风险.
- 急性损伤 (AKI) 是重症患者的常见并发症,但其对COVID-19死亡率的具体影响需要进一步调查.
研究的目的:
- 确定急性损伤 (AKI) 与COVID-19重症患者的死亡率之间的关联.
- 识别其他导致该患者群体死亡率的风险因素.
主要方法:
- 一个单中心病例控制研究在墨西哥重症监护室 (ICU) 进行.
- 分析了2021年1月至12月期间入院的100名危急COVID-19患者.
- 收集的数据包括人口统计,并发症,严重程度得分 (APACHE II,SOFA,NEWS2,CO-RADS),并发症和逗留时间.
主要成果:
- 急性损伤 (AKI) 与增加的死亡率 (调整后几率比 (AOR) 6.64,p = 0.001) 有显著的关联.
- 年龄较大 (>55岁) 和心律不整也是死亡的独立风险因素 (AOR分别为5.3,p=0.007和AOR5.15,p=0.015).
- 与没有AKI患者 (22天) 相比,AKI患者的中位生存时间较短 (15天).
结论:
- 急性损伤 (AKI) 是重症COVID-19患者死亡的主要危险因素.
- 老年和心律失常是额外的显著风险因素.
- 对于COVID-19患者,建议在急诊室入院时进行常规功能查和分期.
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