提供腹腔大动脉化结果对水果和蔬菜摄入量的影响:为期12周的随机第二阶段受控试验
Simone Radavelli-Bagatini1, Catherine P Bondonno2,3, Jack Dalla Via2
1Nutrition & Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia. s.radavellibagatini@ecu.edu.au.
Nature communications
|October 14, 2024
概括
提供血管成像结果并没有改善老年人的饮食,但确实改善了心血管疾病风险因素,如胆固醇水平和整体风险评分. 需要进一步的研究来了解饮食的影响.
科学领域:
- 心血管医学 心血管医学
- 预防性心脏病学 预防性心脏病学
- 医疗成像医学成像
背景情况:
- 非侵入性血管成像结果可以改善心血管疾病 (CVD) 风险因素控制.
- 这些结果对饮食习惯,特别是水果和蔬菜摄入量的具体影响仍然不清楚.
- 了解这种关系对于全面的心血管疾病预防策略至关重要.
研究的目的:
- 为了研究提供腹腔大动脉化结果对老年人饮食摄入量的影响.
- 评估血管成像结果对各种心血管疾病风险因素和生活方式行为的影响.
- 为了确定共享成像发现是否会影响水果和蔬菜的消费.
主要方法:
- 一个为期12周的双臂,单盲,随机对照试验,涉及240名年龄在60-80岁的参与者.
- 参与者被随机分配,接受 (干预) 或不接受 (控制) 他们的腹腔大动脉化结果.
- 主要结局包括水果和蔬菜摄入量的变化,通过血类胡卜素和食物频率问卷进行测量;次要结局涵盖其他饮食方面,身体活动,体重,血压,脂质,葡萄糖,心血管疾病风险评分和药物使用.
主要成果:
- 在主要结局:血中胡卜素和水果和蔬菜摄入量方面,没有观察到群体之间的显著差异.
- 干预组显示血清总胆固醇 (-0.22 mmol/L) 和非HDL胆固醇 (-0.19 mmol/L) 的显著降低.
- 在干预组中,估计的心血管疾病风险得分显著降低 (-0.24%).
结论:
- 向老年人提供非侵入性血管成像结果 (腹腔大动脉化) 并没有改善他们的饮食摄入量,特别是水果和蔬菜的消费.
- 然而,分享这些结果对某些心血管疾病风险因素产生了积极的影响,包括胆固醇水平和估计的心血管疾病风险得分.
- 这些发现表明,虽然血管成像反可能不会直接改变饮食,但它可以有助于更好地管理其他心血管疾病风险指标.
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