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Updated: Jun 10, 2025

Engineering Antiviral Agents via Surface Plasmon Resonance
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Published on: June 14, 2022

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沙尔贝科病毒RBD部分和特定残留物决定了多种ACE2适应性

Jun-Yu Si1, Yuan-Mei Chen1, Ye-Hui Sun1

  • 1State Key Laboratory of Virology, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei, China.

Nature communications
|October 14, 2024
PubMed
概括

具有特定受体结合基因 (RBM) 变化的sarbecoviruses显示出不同的ACE2使用. 长RBM允许广泛的ACE2适应,而删除则缩小或取消它,影响溢出风险.

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