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在癌症进展过程中映射染色体外DNA放大

Hoon Kim1,2,3, Soyeon Kim4,5, Taylor Wade6

  • 1Department of Biopharmaceutical Convergence, School of Pharmacy, Sungkyunkwan University, Suwon-si, South Korea. wisekh@skku.edu.

Nature genetics
|October 14, 2024
PubMed
概括

外染色体DNA (ecDNA) 放大在晚期癌症中更为常见,可能有助于瘤对治疗作出反应. 这些遗传元素,即染色体外DNA (ecDNA),在癌症进展和转移过程中提供了竞争优势.

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