感染性内心炎患者内源性内炎的危险因素
Megh K Shah1, Aretha Zhu1, Aditya Uppuluri1
1Institute of Ophthalmology & Visual Science, Rutgers New Jersey Medical School, Newark, NJ, 07103, USA.
Eye (London, England)
|October 14, 2024
概括
高龄和西班牙裔或亚洲/太平洋岛民种族增加了感染性内心炎 (IE) 患者内源性内眼炎 (EE) 的风险. 糖尿病,酒精使用障碍和肝硬化等疾病也会增加EE风险,而心力衰竭和心律失常会降低EE风险.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- 传染性内心炎 (IE) 是一种严重的感染,影响心脏门.
- 内源性内眼炎 (EE) 是一种严重的眼内感染,可能导致视力丧失.
- 在IE患者中确定EE的风险因素对于早期检测和干预至关重要.
研究的目的:
- 在被诊断患有传染性内心炎 (IE) 的患者中,确定与患内源性内心炎 (EE) 的风险增加相关的人口因素.
- 为了确定可能提高IE患者中EE发展风险的系统性并发症.
主要方法:
- 2002年至2014年国家住院样本 (NIS) 数据库的回顾性分析.
- 使用ICD-9-CM代码识别IE和EE患者.
- 统计分析,包括千平方和逻辑回归,以确定IE患者EE的风险因素.
主要成果:
- 在769,472名IE患者中,2248名 (0.29%) 也患有EE.
- 在21-64岁 (OR, 3.660) 和65岁以上 (OR, 2.852) 的患者中,与0-20岁年龄组相比,观察到EE的风险增加.
- 西班牙裔 (OR, 1.377) 和亚洲/太平洋岛民 (OR, 1.620) 患者比白人患者面临更高的EE风险. 糖尿病 (有/没有并发症),酒精使用障碍 (AUD) 和肝硬化与EE风险增加有关 (ORs 1.433-2.043).
- 相反,充血性心力衰竭 (CHF; OR,0.716),心律失常 (OR,0.678) 和心脏器械 (OR,0.336) 与EE风险降低有关.
结论:
- 高龄 (21岁以上) 和西班牙裔/亚洲裔/太平洋岛民种族是IE患者EE的重要危险因素.
- 糖尿病 (有或没有慢性并发症),AUD和肝硬化显著增加EE风险 (1.5-2倍).
- 心脏不全,心律失常和心脏器械的存在似乎具有保护作用,降低了IE患者的EE风险.
相关概念视频
Endocarditis I: Introduction
2
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
2
Endocarditis II: Clinical features and Diagnostic Tests
2
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
2
Endocarditis III: Medical Management
2
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
2
Endocarditis IV: Nursing Management
2
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
2
Myocarditis I: Introduction
2
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
2
Pericarditis I: Introduction
2
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
2


