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通过单核RNA测序识别出特定于性别的近端管状细胞分化途径

Yueh-An Lu1,2,3, Tanya Smith1,2, Sumukh Deshpande1,2

  • 1Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.

Scientific reports
|October 14, 2024
PubMed
概括

产后脏生长依赖于管状细胞的增殖,而不是新的脏. 这项研究揭示了近端管状细胞 (PTC) 差异化途径导致性别特异性表型,为脏发育和损伤提供治疗点.

关键词:
细胞生物学和细胞结构.慢性脏疾病 慢性脏疾病表面上皮质的 皮质上皮质管是脏中的一个管道.这是一个MRNA和MRNA.靠近的管道 靠近的管道脏上皮细胞是脏上皮细胞.患有脏纤维化脏管状上皮细胞是脏管状上皮细胞.

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RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...