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双边勃起器脊柱平面阻断通过多次注射用于控制 pseudomyxoma peritonei手术中的疼痛:一个单盲随机对照试验

Shuang Yu¹, Guangya Gao¹, Ruiqing Ma²

¹Department of Anesthesiology, Aerospace Center Hospital, No. 15 Yuquan Road, Haidian District, Beijing, 100049, China.

BMC anesthesiology

|October 14, 2024

概括

双边多次注射勃起器脊柱平面阻塞 (ESPB) 在接受手术的伪肌瘤外周 (PMP) 患者中显著减少了疼痛和阿片类药物的使用. 然而,镇痛效果的持续时间受到局部麻醉度的限制.

科学领域:

麻醉学麻醉学
手术瘤学手术瘤学
疼痛管理疼痛管理

背景情况:

伪膜瘤 (PMP) 治疗涉及细胞还原性手术 (CRS) 与高热性腹膜内化疗 (HIPEC),往往导致严重的外科手术期间疼痛.
勃起脊柱平面阻塞 (ESPB) 是一种区域麻醉技术,可以在腹部手术中提供止痛.

研究的目的:

为了比较双边多次注射ESPB与单独全身麻醉在PMP患者的止痛疗效.

主要方法:

50名PMP患者被随机分为两个组:ESPB用全身麻醉 (E组) 和单独全身麻醉 (C组).
在入伍之前,E组在T7和T11级接受了双边ESPB.
主要结局:视觉模拟尺度 (VAS) 在休息状态下得分6小时后输出管. 二次结果:阿片类药物的消费,时间到第一次救援止痛,以及不良事件.

主要成果:

与C组相比,E组在休息和运动期间在多个时间点内显示出明显较低的VAS得分,与C组相比 (P <0.05).
在E组 (P <0.05) 中,手术期间使用雷米芬坦尼尔和手术后救援止痛的需求显著减少 (P <0.05).
在E组 (P < 0.001) 中,第一次救助止痛的时间显著缩短 (P < 0.001).

结论:

双边多次注射ESPB增强了镇痛效果,并减少了PMP患者接受CRS + HIPEC的阿片类药物需求.
治疗ESPB的疼痛缓解时间相对较短,可能归因于所用的局部麻醉剂度较低.

关键词:

勃起器的脊柱平面阻塞块脊柱平面阻塞块手术后的止痛疗法伪瘤 (Pseudomyxoma peritonei) 是一种可能导致瘤的疾病.区域麻醉地区麻醉超声波引导的超声波指导

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