在COPD的COVID-19患者中,使用融合深度学习模型进行严重性评估和核酸转向负时间预测
Yanhui Liu1, Wenxiu Zhang2, Mengzhou Sun3
1Medical Imaging Department, Hohhot First Hospital, Inner Mongolia, P.R. China.
BMC pulmonary medicine
|October 14, 2024
概括
患有肺气和慢性阻塞性肺病 (COPD) 的患者经历了更严重的COVID-19肺炎. 深度学习和放射学准确地预测这些患者的病毒清除时间.
科学领域:
- 肺部医学 肺部医学
- 放射学 放射学是一门学科.
- 人工智能的人工智能
背景情况:
- 慢性阻塞性肺病 (COPD) 增加了COVID-19的严重程度和肺部病变.
- 对于COPD患者的COVID-19预后存在有限的研究,这些患者具有不同的表型.
研究的目的:
- 评估COVID-19严重程度评估的深度学习和放射学.
- 预测COPD表型 (肺,慢性支气管炎) 的COVID-19患者的核酸转阴性时间.
主要方法:
- 对281名COVID-19患者 (95名COVID-19,94名肺气,92名慢性支气管炎患者) 的回顾性分析.
- 胸部CT扫描分析使用U-net进行肺部参与细分.
- 提取了107个放射学特征;使用了斯皮尔曼相关性.
- 深度学习和放射学融合模型开发用于预测核酸转向负时间.
主要成果:
- 肺气的COVID-19显示最低的淋巴细胞数量和最广泛的肺炎.
- 淋巴细胞数与肺部卷入和病毒清除时间相关 (r=-0.145,P<0.05).
- 核聚变模型在预测核酸转向负时间方面取得了80.9%的准确性.
结论:
- 复发性肺炎的肺表型显著恶化COVID-19肺部参与.
- 深度学习和放射学为预测COPDCOVID-19患者的病毒清除时间提供了有价值的工具.
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