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Updated: Jun 10, 2025

High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy
06:38

High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy

Published on: February 7, 2019

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识别具有细胞类型特定DNA结合特征的转录因子

Aseel Awdeh1,2, Marcel Turcotte1, Theodore J Perkins3,4,5

  • 1School of Electrical Engineering and Compute Science, University of Ottawa, 800 King Edward Ave., Ottawa, K1N 6N5, Ontario, Canada.

BMC genomics
|October 14, 2024
PubMed
概括

转录因子 (TFs) 表现出细胞类型特定的DNA结合偏好,挑战了不变结合的假设. 我们的研究表明,结合部位的DNA序列含有许多TFs的显著细胞类型特异性动机.

关键词:
细胞类型的特异性深度学习是一种深度学习.不同的结合差异.转录因子的结合因子

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