通过皮随机噪声刺激和通过皮直流刺激在增强健康个体工作记忆方面的不同有效性:一项随机对照试验
Yukina Tokikuni1, Akihiro Watanabe1, Hisato Nakazono2
1Graduate School of Health Sciences, Hokkaido University, Sapporo, 060-0812, Japan.
Journal of neuroengineering and rehabilitation
|October 14, 2024
概括
跨骨随机噪声刺激 (tRNS) 在健康成年人中改善了工作记忆 (WM) 性能. 这种非侵入性脑刺激技术在基线WM容量较低的个体中显示出更大的益处.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 神经调节是一种神经调节.
背景情况:
- 超直流刺激 (tDCS) 显示出增强工作记忆 (WM) 的前景.
- 对于WM增强的跨骨随机噪声刺激 (tRNS) 存在有限的数据.
- 这项研究比较了tRNS和tDCS对WM的疗效.
研究的目的:
- 调查tRNS对WM性能的有效性.
- 为了将tRNS与tDCS进行比较,并对WM增强进行假刺激.
- 检查基线WM和刺激效益之间的关系.
主要方法:
- 120名健康的成年人参与了一项随机,双盲,假控制的试验.
- 参与者在双重n-back任务中接受了tRNS,tDCS或虚假刺激在左侧脊侧前额皮层 (DLPFC) 上.
- 评估了WM性能 (d-prime) 和反应时间在刺激前,刺激期间和刺激后.
主要成果:
- 在线评估期间,tRNS与虚假相比,显著改善了WM性能 (d-prime).
- 对WM的tRNS的益处在基线WM表现较低的个体中更为明显.
- 在tRNS+DC偏移和tRNS组之间没有发现显著差异.
结论:
- 应用于左侧DLPFC的tRNS有效地提高了健康个体的WM表现.
- 基线WM较低的个体从tRNS中获得更大的好处.
- tRNS为认知增强提供了一个潜在的非侵入性工具,特别是对于认知衰退的人来说.
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