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Updated: Jun 10, 2025

Large-scale Top-down Proteomics Using Capillary Zone Electrophoresis Tandem Mass Spectrometry
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Large-scale Top-down Proteomics Using Capillary Zone Electrophoresis Tandem Mass Spectrometry

Published on: October 24, 2018

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zMAP工具集:通过差异稳定z转换对大规模蛋白质组数据进行基于模型的分析

Xiuqi Gui1, Jing Huang1, Linjie Ruan2

  • 1CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.

Genome biology
|October 14, 2024
PubMed
概括

基于异构标签的质谱测量 (ILMS) 数据集成具有挑战性. zMAP在多次运行中使蛋白质量定量正常化,使细胞分化和癌症研究能够进行强大的蛋白质组分析.

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相关概念视频

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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