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Updated: Jun 10, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
04:01

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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希斯蒂丁酸酶-铁灭酶交叉调节用于有效的肝细胞癌治疗

Yang Qin1, Xiaoli Ling1, Yunxian Li1

  • 1Pharmaceutical and Biomedical Polymers Research Laboratory, Institute of Pharmacy & Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, School of Pharmaceutical Science & MOE Key Lab of Rare Pediatric Disease, Hengyang Medical School, University of South China, Hengyang, 421001, China.

Journal of nanobiotechnology
|October 14, 2024
PubMed
概括

这项研究引入了一种新型的非铁性铁治疗肝癌,通过使用通过前药物输送的miRNA抑制剂来调节Histidine酸酶 (LHPP) 的上升. 这种方法结合化疗和基因疗法来激活铁亡并增强瘤免疫性.

关键词:
铁化是铁化的一种.杰姆西塔的前药物是在 LHPP 中,LHPP 具有较高的度.这是一种miRNA抑制剂.

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Ferritinophagy: Assessing the Selective Degradation of Iron by Autophagy in Human Fibroblasts09:21

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