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血清25-基维生素D水平对四头肌强度的影响:系统性审查和元分析

Michael Tim-Yun Ong¹, Kitson Chun-Kit Tsang², Victor Yan Zhe Lu³

¹Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. michael.ong@cuhk.edu.hk.

BMC sports science, medicine & rehabilitation

|October 14, 2024

概括

更高的维生素D水平与更好的四头肌肌肉力量相关,特别是在老年人和运动员中. 这一发现表明,维生素D补充剂可以支持肌肉功能并降低跌倒风险.

科学领域:

整形外科整形外科整形外科
营养科学营养科学
老年学是一门学科.

背景情况:

维生素D缺乏与肌肉功能障碍和骨关节炎有关.
之前关于维生素D和四头肌强度的研究由于研究设计和混因素而没有结论.
需要进行全面的审查,以澄清血清25-氧维生素D [25(OH) D]与肌肉力量之间的关系.

研究的目的:

系统地审查和对血清25(OH) D水平和四头肌强度的研究进行元分析.
提供对现有证据的综合理解.

主要方法:

在Medline,Embase,CINAHL和SPORTDiscus的系统文献搜索 (2000年后至2024年3月).
包括28项研究 (24项截面,4项纵向) 与5752名参与者.
使用AXIS和QUIPS工具评估研究质量,总体质量为GRADE.

主要成果:

在老年人和运动群体中,在血清25(OH) D水平和180°/s (r=0.245,p=0.004) 的异动力四头肌强度之间发现了显著的正相关性.
没有观察到与60°/s的同度四头肌强度或异动力强度有显著的相关性.
与最大自愿收缩 (MVC) 发现了微弱的负相关性.

结论:

血清25(OH) D水平显示出与异动力学四头肌强度的统计学上显著的正相关性.
较高的维生素D水平可能会降低老年人中跌倒和脆弱性骨折的发生率.
这些发现凸显了维持足够的维生素D水平对肌肉健康的临床重要性.

关键词:

25氧维生素D是一种25-氧维生素.前十字带的重建前十字带的重建进行元分析分析.四头肌强度强度四个四头肌强度.

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