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无导航前列腺DWI的化学转移编码多射击EPI

Yiming Dong¹, David Atkinson², Kirsten Koolstra³

¹C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.

Magnetic resonance in medicine

|October 15, 2024

概括

这项研究引入了一个新的迪克森三射-EPI协议,用于前列腺MRI扩散加权成像 (DWI). 与标准方法相比,它显著减少了几何扭曲,并改善了脂肪抑制,提高了癌症检测.

科学领域:

放射学放射学是一门学科.
医疗成像医学成像
生物物理学的生物物理.

背景情况:

扩散加权成像 (DWI) 对前列腺癌检测至关重要.
标准单射式EPI (ssh-EPI) 存在几何扭曲和脂肪信号干扰.
多射击EPI (mse-EPI) 面临着运动诱导的相变的挑战.

研究的目的:

引入一个无导航器的迪克森三射EPI协议,用于前列腺DWI.
克服ssh-EPI的局限性,包括几何扭曲和脂肪信号干扰.
解决mse-EPI中的相位变化,同时实现水/脂肪分离.

主要方法:

从7名健康志愿者获得的DWI数据使用迪克森3针EPI和标准脂肪抑制ssh-EPI.
通过两个阅读器的利克特尺度评分来比较图像质量.
量化比较的表面扩散系数 (ADC) 值.
将该方案应用于两名患者,以评估临床可行性.

主要成果:

与ssh-EPI相比,迪克森三射EPI显著降低了几何扭曲 (p < 0.01).
没有观察到边缘定义,SNR或整体图像质量的显著差异.
迪克森mse-EPI提供了诸如B0地图驱动的扭曲校正和优越的脂肪抑制等优势.
病变在患者数据中的ADC地图上的两个协议中都清晰可识别.

结论:

拟议的迪克森三次射击EPI协议是前列腺DWI的ssh-EPI的一个有希望的替代方案.
它提供了减少的几何扭曲和改进的脂肪抑制.
该协议解决了常见的DWI问题,并增强了扫描灵活性,以优化成像.

关键词:

化学转移编码编码化学转移编码扩散扩散是一种扩散.多次拍摄的 EPI.前列腺前列腺前列腺结构化的低级别.

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