在心脏粉样蛋白和末期脏病患者中比较心声图谱应变成像

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Updated: Jun 10, 2025

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

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Taylor Ferris¹, Ethan Yohannan², Kurt Daniel³

¹Department of Internal Medicine, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, USA.

Echocardiography (Mount Kisco, N.Y.)

|October 15, 2024

概括

在末期脏疾病 (ESRD) 患者中,对诊断心脏粉样性病 (CA) 的特异性并不适用. 这一发现质疑这种成像模式在ESRD人群中对CA诊断的临床实用性.

科学领域:

心脏病学心脏病学
医疗成像医学成像
腎臟病學 (nephrology) 是一種醫學專業.

背景情况:

由于非特异性症状和心声回声学发现,诊断心脏粉症 (CA) 是具有挑战性的.
角节约菌株模式已被提议作为CA的诊断标志物.
这种模式在区分CA与其他疾病,如末期脏病 (ESRD) 的特异性尚不清楚.

研究的目的:

为了比较心脏粉样性病 (CA) 和末期病 (ESRD) 患者之间的应变模式.
评估角节约性菌株模式在区分CA和ESRD的诊断效用.

主要方法:

在25名CA患者 (CKD阶段≤3) 和19名ESRD患者 (CA阴性) 中比较了心声谱纵向应变 (LS) 参数.
使用平均顶点LS除以平均中和基底LS的和计算相对顶点LS.
分析了区域和全球的LS,心声和人口参数.

主要成果:

在CA和ESRD组之间,在区域或相对的顶端菌株中没有观察到显著差异.
相对的顶端应变比>1显示了80%的灵敏度,但对CA的特异性只有42%.
视觉评估揭示了所有组中的尖端节约菌株模式.

结论:

末期病 (ESRD) 呈现与心脏粉样性病 (CA) 叠加的成像发现.
在ESRD患者中,相对的角节约菌株对CA是非特异性的.
在ESRD中对CA的临床诊断应依赖于强烈的临床怀疑和其他成像/人口学变量,而不仅仅依赖于尖端节省模式.

关键词:

欧洲发展与发展委员会 (ESRD)顶端的节省性节制性.心脏的粉样蛋白.压力压力压力压力

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