一般肥胖和前列腺癌与腹部肥胖和族群相关:美国基于人口的跨部门研究
Anwar E Ahmed1, Callista B Martin2, Bassam Dahman3
1Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Research and reports in urology
|October 15, 2024
概括
一般肥胖本身并不会显著增加前列腺癌的风险. 然而,腹部肥胖与黑人和白人男性更高的前列腺癌几率有关,在黑人男性中观察到的结合肥胖效应.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 关于一般肥胖和前列腺癌风险的证据是不一致的.
- 这项研究调查了腹部肥胖和种族对这种关联的影响.
研究的目的:
- 为了确定腹部肥胖是否会改变一般肥胖和前列腺癌之间的关系.
- 检查肥胖和前列腺癌之间的关系的种族差异.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) 的数据.
- 分析了10,683名白人和6,020名非西班牙裔黑人男性的数据.
- 按体重指数 (BMI) ≥30定义的肥胖和按腰围 (WC) ≥102厘米的腹部肥胖.
主要成果:
- 总体而言,肥胖和非肥胖男性之间前列腺癌患病率没有显著差异.
- 腹部肥胖与黑人和白人男性的前列腺癌几率增加有显著的关联.
- 综合的一般和腹部肥胖症在黑人男性中增加了前列腺癌的几率,但不是白人男性.
结论:
- 一般肥胖和前列腺癌之间的关联受腹部肥胖和种族的影响.
- 综合的一般和腹部肥胖可能是一个可修改的因素,以减少前列腺癌结果的种族差异.
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