脚和膝盖变形与功能限制和发生性关节炎有关:前性队列研究
Jonathan K L Mak1,2, Kathryn Choon Beng Tan3, Janus Siu Him Wong4
1Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, China.
Osteoporosis and sarcopenia
|October 15, 2024
概括
足部疼痛与中国成年人的功能限制和下降有关. 然而,大腿关节炎会增加患骨关节炎 (OA) 的风险,特别是在老年,女性或肥胖个体中.
科学领域:
- 整形外科 整形外科 整形外科
- 类风湿病学 类风湿病学
- 老年学是一门学科.
背景情况:
- 脚和腿部疾病很常见,可能会影响流动性和生活质量.
- 骨关节炎 (OA) 是一种普遍的退行性关节疾病,通常影响下肢.
- 了解脚/腿健康和功能衰退之间的相互作用对于公共健康至关重要.
研究的目的:
- 调查脚和腿症状,结构和功能与功能限制和骨关节炎 (OA) 之间的关联.
- 检查特定的脚和膝关节问题与功能结果和OA发展之间的横截面和纵向关系.
主要方法:
- 来自香港骨质疏松症研究的1253名香港华裔成年人的队列接受了足部姿势,功能,疼痛和形 (形,膝盖形) 的检查.
- 后勤回归分析了与功能结果 (步行速度,跌倒,限制) 的横截面关联以及普遍存在的OA.
- 与电子健康记录相关的考克斯模型评估了8年来与发生性OA的关联,并根据年龄,性别和BMI进行了调整.
主要成果:
- 患病率:高症 (33.1%),脚痛 (35.1%),膝盖疼痛 (25.8%).
- 足部疼痛与功能限制和经常性跌倒显著相关,并且在基线时患有OA,但没有发生OA.
- 瓦鲁斯膝关节显示,发生性OA的风险增加了3倍,特别是在老年人,女性和肥胖个体中.
结论:
- 在社区生活的中国成年人中,脚痛是功能限制和跌倒的重要预测因素.
- 在这个群体中,脚形与功能限制或跌倒没有直接联系.
- 瓦鲁斯膝盖是发生性骨关节炎的显著危险因素,特别是在特定的人口群体中.
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