代谢阶段特异性修改营养风险在重病得分中的应用:在重病患者中的前性观察性研究
Geon Ho Lee1, Ye Ju Kim1, So Hyang Park1
1College of Pharmacy, Korea University, Sejong, Republic of Korea.
Frontiers in nutrition
|October 15, 2024
概括
营养不良在ICU中很常见. 一个特定阶段的修改营养危险在重症患者 (mNUTRIC) 评分有助于指导营养支持,改善了重症患者的结果.
科学领域:
- 关键护理医学 关键护理医学
- 临床营养学 临床营养学
- 营养支持营养支持
背景情况:
- 由于营养摄入/吸收和炎症不佳,重症监护室 (ICU) 中营养不良的高患病率.
- 催化作用限制了营养供应,导致营养不良;代谢状态决定了适当的营养.
- 目前的营养支持策略缺乏特定阶段的考虑.
研究的目的:
- 建立一个特定阶段的营养支持战略.
- 为不同的代谢阶段实施修改的重症患者营养风险 (mNUTRIC) 评分.
主要方法:
- 成年ICU患者的前性观察研究 (n=613急性阶段,n=361晚期).
- 在急性 (2日) 和晚期 (7日) 阶段评估营养 (mNUTRIC评分),临床数据和营养供应 (卡路里,蛋白质).
- 使用后勤和考克斯回归分析了营养供应和28天死亡率之间的关系.
主要成果:
- 在急性和晚期阶段的高mNUTRIC得分与28天死亡率相关.
- 死亡的独立风险因素包括高的mNUTRIC评分,乳酸盐升高,低白蛋白,瘤,透析 (急性阶段) 和低卡路里充足 (晚期).
- 危险比率表明与这些因素相关的重大风险.
结论:
- mNUTRIC评分有效地识别了受益于营养支持的ICU患者.
- 在这两个阶段,对于高mNUTRIC分数的患者来说,营养供应至关重要.
- 建议在急性阶段提供谨慎的营养供应,并在晚期提供足够的供应.
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