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Updated: Jun 10, 2025

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
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Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

Published on: August 11, 2017

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通过向瘤微环境来克服EGFR-TKI耐药性

Jinsong Zhang1, Natalie Vokes2, Man Li1

  • 1State Key Laboratory of Molecular Oncology, CAMS Key Laboratory of Translational Research on Lung Cancer, Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuannanli, Chaoyang District, Beijing 100021, China.

Chinese medical journal pulmonary and critical care medicine
|October 15, 2024
PubMed
概括

在非小细胞肺癌 (NSCLC) 中,对表皮生长因子受体 (EGFR) - 铁氨酸激酶抑制剂 (TKIs) 的耐药性是一个重大挑战. 本综述探讨了抵抗机制,重点关注瘤微环境和克服TKI抵抗的策略.

关键词:
药物耐药性 药物耐药性 药物耐药性皮肤表皮生长因子受体.皮肤上生长因子受体-铁氨酸激酶抑制剂.非小细胞肺癌是非小细胞肺癌.瘤微环境是一个微环境.

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Published on: April 6, 2016

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