m6A阅读器IGF2BP1通过促进TUBB4BmRNA稳定促进肝星细胞的激活,从而促进肝星细胞的激活

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Yanshan Li1, Ling Chen1, Shuyi Li1

  • 1School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.

Journal of gastroenterology and hepatology
|October 15, 2024
PubMed
概括

胰岛素样生长因子-2 mRNA结合蛋白1 (IGF2BP1) 通过稳定 TUBB4B 在激活的肝星细胞中驱动肝纤维化. 准IGF2BP1/TUBB4B/FAK轴为肝纤维化提供了一个潜在的治疗策略.

关键词:
这就是IGF2BP1的原因.在TUBB4B中使用.肝脏的恒星细胞.m6A 一个很好的.梅本达 (Mebendazole) 是一种一种

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