设计,合成和生物评估海洋纳夫托基-纳夫托衍生物作为潜在的抗癌剂

Yujuan Li1, Luyou Yelv1, Xiaoqiu Wu1

  • 1Department of Chemistry, College of Food Science and Technology, Shanghai Ocean University, Shanghai, China.

概括

一种新型的纳夫托基诺-纳夫托衍生物,化合物13,通过诱导细胞亡和抑制细胞增殖,显示出强大的抗癌活性. 这种化合物向EGFR/PI3K/Akt通路,表明其作为一种新的癌症治疗的潜力.

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