Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Asymmetric Lipid Bilayer01:35

Asymmetric Lipid Bilayer

Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...
Bioavailability Enhancement: Drug Permeability Enhancement01:27

Bioavailability Enhancement: Drug Permeability Enhancement

After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt secretion,...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

DNA cube-gated ratiometric ECL/SERS biosensor for APE1 via HCR-driven interfacial reconstruction.

Biosensors & bioelectronics·2026
Same author

Dual-mode ECL/SERS ratiometric sensing of 3CLpro via enzyme-gated, entropy-driven DNA assembly on CsPbBr₃@PDA@Au.

Colloids and surfaces. B, Biointerfaces·2026
Same author

Self-validated SARS-CoV-2 detection via an automated DNA molecular machine-regulated ECL/SERS signal switching platform.

Biosensors & bioelectronics·2026
Same author

Aptakiss-guided CRISPR/Cas13a signal amplification for ultrasensitive FEN1 detection using CsPbBr<sub>3</sub>@PDA@AuNPs-based electrochemiluminescence platform.

Biosensors & bioelectronics·2026
Same author

Cube-track encoded dual-mode ECL/SERS biosensor for ultrasensitive NF-κB p50 detection via transcription-DSN cascade.

Biosensors & bioelectronics·2026
Same author

Development of machine perfusion strategies for liver support and beyond.

Journal of advanced research·2026

相关实验视频

Updated: Jun 22, 2026

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins
00:11

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Published on: August 31, 2019

23.7K

开发用于肝脏疾病的细胞膜相关脂质体.

Dongxue Ge1, Ran An1, Lingling Xue1

  • 1Division of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing 210008, China.

ACS nano
|October 15, 2024
PubMed
概括
此摘要是机器生成的。

细胞膜相关的脂质体为肝脏疾病提供了有前途的药物输送. 需要进一步的研究来优化它们的使用,并克服治疗肝病理的临床挑战.

关键词:
申请申请表 申请表细胞膜的细胞膜.交付策略 交付策略互动 互动 互动 互动脂质细胞体中的脂肪体.肝脏疾病是一种肝脏疾病.准备 准备 准备目标化 目标化 目标化

更多相关视频

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes
09:51

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Published on: March 3, 2020

9.0K
Preparation, Administration, and Assessment of In Vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes
08:44

Preparation, Administration, and Assessment of In Vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes

Published on: July 30, 2020

4.3K

相关实验视频

Last Updated: Jun 22, 2026

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins
00:11

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Published on: August 31, 2019

23.7K
Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes
09:51

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Published on: March 3, 2020

9.0K
Preparation, Administration, and Assessment of In Vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes
08:44

Preparation, Administration, and Assessment of In Vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes

Published on: July 30, 2020

4.3K

科学领域:

  • 生物医学工程 生物医学工程
  • 药物输送系统 药物输送系统
  • 肝病学 肝病学是一种肝病学.

背景情况:

  • 肝脏疾病正在增加,目前药理治疗的有效性有限.
  • 脂质体增强药物输送到目标部位,提高治疗效果.
  • 细胞膜相关的脂质体显示出潜力,但需要更深入地了解它们的结合机制.

研究的目的:

  • 对肝病治疗的细胞膜相关脂质体进行审查.
  • 总结它们的组成,类型,结构和药物输送策略.
  • 讨论临床应用,挑战和未来前景.

主要方法:

  • 关于细胞膜相关脂质体的综合文献综述.
  • 分析它们的结构,组成和药物输送机制.
  • 对治疗肝病的临床应用和挑战的评估.

主要成果:

  • 细胞膜相关的脂质体为肝脏病理提供了增强的药物向.
  • 使用这些脂质体,存在各种药物输送策略.
  • 除了现有的临床挑战之外,还确定了重要的潜在益处.

结论:

  • 细胞膜相关的脂质体显示出改善肝病治疗的前景.
  • 进一步的研究对于优化它们的利用和解决临床障碍至关重要.
  • 概述了未来的发展方向,以提高治疗结果.