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通过Argali介导的基因流动,在绵羊物种之间深度的祖先入侵塑造了绵羊基因组
Feng-Hua Lv1, Dong-Feng Wang2,3, Si-Yi Zhao1
1Frontiers Science Center for Molecular Design Breeding (MOE), State Key Laboratory of Animal Biotech Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Molecular biology and evolution
|October 15, 2024
概括
绵羊和野生亲属之间的遗传侵入是复杂的. 这项研究揭示了北美帕奇西里形动物通过argali间接侵入巴希拜羊,澄清了进化场景.
科学领域:
- * 进化遗传学的进化遗传学
- * 动物基因组学
- * 种类化和杂交化
背景情况:
- * 在Ovis物种中广泛的遗传内入影响了适应和特征.
- * 家畜羊与野生相亲之间的杂交的进化途径尚未完全理解.
- * 区分直接和间接的内侵事件是具有挑战性的.
研究的目的:
- * 阐明家畜羊与其野生亲属之间的杂交复杂的进化场景.
- * 调查涉及argali,Pachyceriforms和家禽羊品种的内侵历史.
- *使用基因组数据区分直接和间接的内侵事件.
主要方法:
- * 整合了来自羊,argali,大角羊,雪羊和羊的参考基因组.
- *分析了来自169只家养绵羊群和6只野生亲属群的856个完整基因组.
- *全面的基因组分析来测试和推断内进事件.
主要成果:
- * 推断阿加利血统的起源大约在3.083.35万年前.
- * 估计argali和Pachyceriform祖先 (例如,大角羊,雪羊) 之间的杂交在156万年前.
- * 解决了 Pachyceriforms 显然直接侵入 Bashibai 羊的问题,因为它通过 argali 间接侵入.
结论:
- * 绵羊和野生动物相对杂交的进化历史是复杂的,涉及多个内侵事件.
- *间接的内侵,例如通过像argali这样的中间物种,起着重要的作用.
- *基因组分析可以成功地解开复杂的内侵历史,区分直接和间接的途径.
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