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一个用于定量T2*胎儿身体MRI和低场细分的自动化管道

Kelly Payette^1,2, Alena Uus^1,2, Jordina Aviles Verdera^1,2

¹Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention

|October 15, 2024

概括

低场胎儿MRI提供了先进的成像,减少了文物和更广泛的访问. 一个新的半自动管道允许快速,详细的T2*放松计和器官细分用于胎儿身体分析.

科学领域:

医疗成像医学成像
生物物理学的生物物理.
围产期健康围产期健康

背景情况:

低场 (0.55T) 核磁共振正在为胎儿成像而出现,这是由于其减少文物和更广泛的孔径访问等好处.
目前的局限性包括缺乏用于细分和重建的自动图像处理工具.

研究的目的:

引入一个半自动定量MRI管道用于低场强度的胎儿身体分析.
为了使主要胎儿器官的快速和详细的定量T2*放松计.

主要方法:

获得胎儿身体的多回声动态序列.
在高分辨率的3D体积中使用可变形切片对体积重建进行重建.
开发一个半监督的神经网络,用于自动细分10个胎儿器官.

主要成果:

成功生成结构和定量T2* 3D卷.
在10个细分器官中的8个中,获得的子值>0.74.
在肺部,肝脏和脏 (R2 > 0.5) 中,T2*值和妊娠年龄 (GA) 之间存在强烈的关系.

结论:

开发的管道允许在广泛的GA范围内 (17-40周) 对胎儿进行先进的MRI分析.
这种方法是强大的动作文物和可行的临床扫描.
低场胎儿MRI是围产期健康的一个有希望的工具.

关键词:

胎儿的核磁共振成像低电场是一个低电场.在T2*上使用.

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