鼻腔和鼻鼻腔中壮病的可变解剖特征:对内镜内外形外科手术的影响
Kento Takahara1, Ryota Tamura2, Erika Isomura3
1Department of Neurosurgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku- ku, Tokyo, 160-8582, Japan.
Acta neurochirurgica
|October 15, 2024
概括
巨病患者具有明显的鼻腔解剖学,包括更长的鼻孔到背部的角距离和更窄的鼻动脉间距. 这些解剖学上的差异,以及鼻腔和骨的缩,可能会使内镜内鼻腔跨形手术复杂化.
科学领域:
- 神经外科 神经外科
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
背景情况:
- 分泌生长激素 (GH) 的垂体神经内分泌瘤 (PitNETs) 会导致壮症.
- 内透视内透视透视的方法 (EEA) 是PitNET去除的标准方法.
- 关于鼻腔形态的定量数据是有限的.
研究的目的:
- 为了评估鼻腔和鼻鼻腔的解剖特征在壮病患者.
- 将这些特征与患有非功能性PitNETs的患者的特征进行比较.
- 评估GH/IGF-1水平与鼻腔解剖之间的相关性.
主要方法:
- 术前CT扫描的回顾性分析.
- 对20名壮病患者 (GH分泌PitNET) 和22名对照患者 (非功能PitNET) 的比较.
- 测量鼻腔和鼻 sinus 的尺寸.
主要成果:
- 宏壮壮症组显示鼻孔到背部的腰部距离显著更长 (p=0.0022).
- 壮症组在状内动脉之间的距离显著缩短 (p=0.0092).
- 观察到鼻腔粘膜和骨增大;GH水平与形孔径宽度相关 (p=0.0171).
结论:
- 巨症与特定的鼻腔和鼻副鼻腔解剖变化有关.
- 这些变化可能会在EEA手术期间带来挑战.
- 优化状鼻前部的外科走廊对于成功的结果至关重要.
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