微塑料,木材和玻璃被抗微生物耐药和致病细菌的选择性殖民
Emily M Stevenson1,2,3, Owen Rushby-Jones2, Angus Buckling2
1European Centre for Environment and Human Health, Environment and Sustainability Institute, University of Exeter Medical School, Faculty of Health and Life Sciences, Penryn Campus, Cornwall, UK.
Microbiology (Reading, England)
|October 15, 2024
概括
微塑料和天然基质可以丰富抗微生物耐药 (AMR) 细菌,粒子特征影响殖民. 这突显了与Plastisphere相关的风险和AMR病原体的潜在传播.
科学领域:
- 环境微生物学环境微生物学
- 塑料污染问题 塑料污染问题
- 抗微生物耐药性 (AMR) 是一种
背景情况:
- 塑圈,塑料碎片上的微生物群落,可能是病原性和AMR细菌的庇护所.
- 以前的研究往往缺乏适当的控制,限制了对AMR病原体传播的微塑料特异性风险的理解.
- 需要证据来确认微塑料是否独特地丰富和传播AMR细菌.
研究的目的:
- 调查AMR细菌和致病性大肠杆菌 (ExPECs) 对微塑料和天然基质的选择性殖民.
- 将不同聚合物类型,来源和形态的AMR和ExPEC患病率与天然和惰性基质进行比较.
- 评估颗粒表面粗度对AMR殖民化的影响.
主要方法:
- 使用培养和分子方法 (定量聚合酶连锁反应 (qPCR)) 来确定AMR流行率.
- 使用多重殖民地PCR来识别肠外致病原体大肠杆菌 (ExPECs).
- 对环境样本的微塑料 (聚乙烯,聚乙烯),天然基板 (木材),惰性基板 (玻璃) 和对照物的比较殖民.
主要成果:
- 聚钢和木材颗粒显著丰富了AMR细菌.
- 来自污水的生物珠特别丰富的ExPECs.
- 颗粒的粗性影响了殖民,像聚钢和木材这样的不太光滑的颗粒显示出更高的AMR丰富;聚乙烯的表面风化没有显著改变AMR流行率.
结论:
- 基质特定的特征,特别是表面粗度,增强了AMR和致病细菌对塑料和自然颗粒的殖民.
- 塑圈与自然基板一起,可以作为AMR细菌的储存库.
- 这些发现强调,在评估水生环境中AMR传播风险时,需要仔细考虑基质特性.
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