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Updated: Jun 10, 2025

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通过SHP1/BTK轴抑制脂肪酸氧化,TREM2会加剧败血症

Siqi Ming1,2, Xingyu Li1,3, Qiang Xiao4

  • 1Center for Infection and Immunity and Guangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.

The Journal of clinical investigation
|October 15, 2024
PubMed
概括

在骨髓细胞2 (TREM2) 上表达的触发受体抑制了败血症中的脂肪酸氧化 (FAO). 抑制TREM2通过恢复FAO改善败血症结果,提供潜在的治疗点.

关键词:
脂肪酸氧化过程中的脂肪酸氧化.传染性疾病传染性疾病.

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