合成和生物评估的isoaurone衍生物作为抗炎剂的代理商

Xueqian Bai1, Chao Ye1, Zhe Liu1

  • 1Jilin Medical University, Jilin, 132013, PR China.

Chemistry & biodiversity
|October 15, 2024
PubMed
概括

新的含有1,2,4-triazole部分的异氨衍生物被合成并测试其抗炎作用. 化合物14e显示出强大的,剂量依赖的氧化和环氧化酶-2 (COX-2) 上调的抑制,表明其作为主要抗炎剂的潜力.

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