营养对切除术后瘤发病率和死亡率的影响:营养指数的系统审查和元分析
Katherine Pierce1, Jeremy Gaskins2, Robert C G Martin Ii1
1Division of Surgical Oncology, The Hiram C. Polk, Jr., M.D. Department of Surgery, University of Louisville School of Medicine, Louisville, KY 40292, United States.
Nutrition reviews
|October 15, 2024
概括
营养指数预测了癌症手术后的结果,组合类型和上部胃肠道瘤的准确性更高. 综合多个因素的综合指数为预测整体存活率提供了最为临床的实用性.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 营养科学 营养科学
背景情况:
- 对于接受实体瘤切除的患者来说,营养状况至关重要.
- 存在各种营养指数,对术后结果具有不同的预测能力.
研究的目的:
- 综合评估常用的营养指数.
- 评估它们对术后并发症 (POCs),无复发存活率 (RFS) 和整体存活率 (OS) 的预测能力.
主要方法:
- 对14个营养指数进行系统审查 (2015年1月至2022年7月).
- 分析分析以评估基于索引类型,瘤部位和患者状态的OS预测能力.
- 分析了38篇关于23,970名患者的文章.
主要成果:
- 营养指数预测较低的OS (HR 2.14).
- 上部胃肠道瘤比下部胃肠道或其他部位更具预测性.
- 综合指数比表型指数更具预测性 (HR 2.47与1.73).
结论:
- 预测效果取决于指数类型,瘤部位和结果.
- 营养状况是上部肠道切除中OS的重要预测因素.
- 整合表型,代谢和免疫因素的综合指数提供了更大的临床实用性.
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