相关实验视频

Updated: Jun 10, 2025

Analysis of Endocytic Uptake and Retrograde Transport to the Trans-Golgi Network Using Functionalized Nanobodies in Cultured Cells
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Analysis of Endocytic Uptake and Retrograde Transport to the Trans-Golgi Network Using Functionalized Nanobodies in Cultured Cells

Published on: February 21, 2019

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泰蛋白是跨戈尔吉网络分泌途径的RAB依赖媒介

Anirban Baral1, Delphine Gendre1, Bibek Aryal1

  • 1Department of Forest Genetics and Plant Physiology, Umeå Plant Science Centre, Swedish University of Agricultural Sciences, Umeå 901 87, Sweden.

The Plant cell
|October 15, 2024
PubMed
概括

研究人员确定了TYPHON 1 (TPN1) 和TYPHON 2 (TPN2) 蛋白质对于植物发育至关重要. 这些蛋白质抑制了ech突变的缺陷,揭示了跨戈尔吉网络贩运和阿拉比多普西斯中辅酶运输的新见解.

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Reconstitution of Msp1 Extraction Activity with Fully Purified Components

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Rab GTPases act in a regulated cascade during membrane fusion, helping the lipid bilayers mix. The Rab family of proteins are active when bound to GTP, and inactive when bound to GDP. Hence, they act as guanine nucleotide-dependent molecular switches. Rab-GTP recognizes and binds to long or short-range tethering proteins to capture the target vesicle. These tethers coordinate with SNAREs on the vesicle and the target membrane to assemble the trans SNARE complex that locks the mixing bilayers.
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