在评估预防早产干预的随机对照试验后长期儿童随访:系统性审查
Larissa I van der Windt1, Noor E Simons1, Annemijn A de Ruigh1
1Department of Obstetrics and Gynaecology, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands; Amsterdam Reproduction and Development Research Institute, Amsterdam, The Netherlands.
European journal of obstetrics, gynecology, and reproductive biology
|October 15, 2024
概括
很少有随机对照试验 (RCT) 评估早产预防,包括长期儿童发育结果. 然而,长期跟踪在超过三分之一的研究中显著改变了结论,突出了对标准实践的需求.
科学领域:
- 产科和妇科 产科和妇科
- 发育儿科 发育儿科
- 临床试验方法论 临床试验方法论
背景情况:
- 为预防早产而进行的产科干预可能会对儿童发育产生意想不到的长期影响.
- 目前的研究往往缺乏对这些长期发育结果的标准评估.
结论:
- 研究早产预防干预措施的RCT中很少包含长期儿童发育评估.
- 尽管频率低,但长期随访数据改变了研究结论在大量情况下 (大约三分之一).
- 实施常规的长期后续研究对于准确地告知父母有关干预措施对儿童的潜在影响至关重要.
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