复杂骨发育不良患者中气管切除术的发生率:32年的机构经验
Seth C Eckhardt1, Clare M Richardson2, Klane K White3
1Department of Otolaryngology Head and Neck Surgery, University of Washington School of Medicine, Seattle, WA, USA.
International journal of pediatric otorhinolaryngology
|October 15, 2024
概括
几乎一半的患有需要呼吸道干预的骨发育不良的儿科患者接受了气管切除术. 在这些患者中,呼吸不全是常见的,复杂的挑战.
科学领域:
- 儿科肺病学 儿科肺病学
- 医学遗传学 医学遗传学
- 手术气道管理手术气道管理
背景情况:
- 骨发育不良会导致多层次的气道损害,导致复杂的呼吸挑战.
- 操作性气道评估和气管切除术是严重病例的关键干预措施.
研究的目的:
- 为了确定骨发育不良的子组,经常需要操作性呼吸道干预和气管切除术的放置.
- 描述这些患者的临床过程.
主要方法:
- 对患有骨发育不良和呼吸道干预的儿科患者的回顾性审查 (1990-2022年).
- 排除没有明确的骨发育不良症患者,具有突综合征或有限的数据的患者.
- 对人口统计,并发症和呼吸道干预的描述性统计分析.
主要成果:
- 41名骨发育不良患者接受了呼吸道干预; 19名 (46%) 接受了气管切除术.
- 骨发育不良率较高的骨发育不良群体包括 纤维素和相关疾病,硫化障碍和孔德罗发育不良点性.
- 气管切除术是在1.8岁的中位年龄开始的;只有4名患者成功地脱.
结论:
- 接受呼吸道干预的骨发育不良患者中,近一半的患者需要进行气管管切除术.
- 呼吸不足和复杂的气道管理是骨发育不良的显著表现.
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