内科病房的低肌肉质量:流行率和生存影响
Luis Andrés González-Torres1, Víctor Daniel Acuña-Rocha1, Mario Herrera-Nuñez1
1Departamento de Medicina Interna, Facultad de Medicina y Hospital Universitario, Dr. José E. Gonzalez, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
Archives of medical research
|October 15, 2024
概括
几乎一半的内科患者的肌肉质量指数 (LMI) 较低,这种情况与较高的死亡率和再入院率有关. 男性和女性的特定LMI切割值可以预测长期生存结果.
科学领域:
- 老年医学 老年医学
- 内部医学 内部医学
- 放射学 放射学是一门学科.
- 临床营养学 临床营养学
背景情况:
- 低肌肉质量在住院患者中普遍存在,但其对非手术内科患者的影响仍未得到充分研究.
- 低肌肉质量的现有诊断标准不一致,导致报告的患病率存在很大差异.
- 这项研究解决了关于低肌肉质量的文献中非手术患者的不足.
研究的目的:
- 为了确定入院内科病房的患者低肌肉指数的患病率.
- 调查低肌肉指数与临床结果之间的关联,包括死亡率和再入院.
主要方法:
- 预计将招募107名患者,这些患者在内科病房接受腹部CT扫描.
- 在L3腰椎水平评估骨肌肉质量指数 (L3MI).
- 评估主要结果 (低L3MI的流行) 和次要结果 (医院死亡率,住院时间,医院感染,再入院).
主要成果:
- 在受研究的人群中,低L3MI的患病率为46.7%.
- 特定的L3MI切割值 (男性为46.3cm2/m2,女性为40.9cm2/m2) 显示了预测一年死亡率的价值 (AUC为0.62-0.63).
- 低L3MI的患者在医院死亡率,60日,90日,360日死亡率和医院再入院率显著增加.
结论:
- 低肌肉质量指数影响到近一半的患者入院内科病房.
- 对于男性和女性来说,已确定的L3MI截止值可以预测显著的临床结果,包括12个月死亡率.
- 这些发现强调了评估内科病人的肌肉质量的临床重要性.
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