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预测患有多发性硬化症的人使用多发性硬化症步行尺度-12预测倒闭状态.

Caterina Abate1, Elizabeth S Gromisch2, Marc Campo1

  • 1Mercy University, 555 Broadway, Dobbs Ferry, NY, USA.

Multiple sclerosis and related disorders
|October 15, 2024
PubMed
概括

多发性硬化症步行量表 (MSWS-12) 可以识别患有多发性硬化症 (MS) 的个体,这些个体有更高的跌倒风险. 在MSWS-12中得分为46%或更高,表明患病的可能性增加.

关键词:
布 布 布 的 布 布 的在MSWS-12中使用.多发性硬化症是多发性硬化症.查工具 查工具步行 走路 走路

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科学领域:

  • 神经学 神经学
  • 康复科学科学 康复科学
  • 临床评估 临床评估

背景情况:

  • 患有多发性硬化症 (PwMS) 的人面临较高的跌倒风险.
  • 有效的选工具对于识别易摔倒的PwMS至关重要.
  • 这项研究旨在验证MSWS-12作为跌倒查工具.

研究的目的:

  • 建立MSWS-12的截止分数,以确定PwMS中的失败者.
  • 评估MSWS-12对落户状态的预测准确度.
  • 评估MSWS-12的预测能力,同时控制混因素.

主要方法:

  • 171个PwMS公司完成了MSWS-12并报告了过去六个月的下降.
  • 跌倒者被定义为报告一次或多次跌倒.
  • 接收器运行特征 (ROC) 曲线分析确定了分类准确性 (AUC).
  • 对年龄,性别,BMI,疾病持续时间和疲劳进行控制的后勤回归.

主要成果:

  • 在MSWS-12中,对于落者 (AUC = 0.74) 证明了合理的分类准确性.
  • 截止值分数≥46%产生了76.1%的灵敏度和64.6%的特异性.
  • 在MSWS-12得分 (aOR: 3.77) 和疲劳 (aOR: 1.11) 显著预测了摔倒状态.

结论:

  • 在MSWS-12上PwMS得分≥46%的人更有可能成为失败者.
  • 在MSWS-12显示潜在的作为一个有价值的查工具,以降低风险在MS.
  • 临床判断和其他评估可以提高MSWS-12的实用性.