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Updated: Jun 19, 2026

siRNA Screening to Identify Ubiquitin and Ubiquitin-like System Regulators of Biological Pathways in Cultured Mammalian Cells
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多模式屏幕识别了噪声调节蛋白.

Óscar García-Blay1, Xinyu Hu1, Christin L Wassermann2

  • 1Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, the Netherlands; Oncode Institute, Nijmegen, the Netherlands.

Developmental cell
|October 15, 2024
PubMed
概括

科学家们发现了调节基因表达噪声的蛋白质,独立于平均表达水平. SON蛋白控制着转录噪声,影响细胞命运决策而不改变平均基因活性.

关键词:
一个儿子,一个儿子.细胞的命运选择,细胞的命运选择.不同化的差异化差异化.胚胎干细胞是一种胚胎干细胞.基因表达的变异性.在mRNA处理过程中.噪音监管 噪音监管 噪音监管单细胞转录组学 单细胞转录组学随机噪声 随机噪声是指随机的噪声.

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Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
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