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风湿性关节炎患者焦虑和抑郁的趋势:基于人口的研究
Rachel E Giblon1, Sara J Achenbach2, Elena Myasoedova3
1R.E. Giblon, MS, Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
患有类风湿性关节炎 (RA) 的个人表现出越来越多的焦虑和同时出现的焦虑和抑郁症. 这种心理健康差距随着时间的推移而扩大,特别是在血清阳性RA患者中,需要临床关注.
科学领域:
- 类风湿病学 类风湿病学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 风湿性关节炎 (RA) 是一种慢性自身免疫性疾病.
- 精神健康并发症,如抑郁症和焦虑症在RA患者中很常见.
- 了解这些并发症的时间趋势对于患者护理至关重要.
研究的目的:
- 研究患有类风湿性关节炎 (RA) 的人群中抑郁症和焦虑症诊断的30年趋势.
- 为了比较RA患者和匹配的非RA对照之间的这些趋势.
- 在RA中确定具有最明显趋势的特定患者群体.
主要方法:
- 使用罗切斯特流行病学项目的回顾性队列研究.
- 包括发生的RA患者 (1985-2014) 与非RA对照组匹配1:1.
- 通过ICD代码定义的抑郁和焦虑的诊断;Cox模型用于分析几十年来的趋势.
主要成果:
- 在RA和非RA组中,从2005-2014年与1985-1994年相比,观察到焦虑和同时出现的焦虑和抑郁症的时间增加.
- 与对照人群相比,RA患者表现出焦虑的增加,同时出现焦虑和抑郁.
- 这种趋势在血清阳性RA患者中最为明显,焦虑的危险比率显著更高.
结论:
- 焦虑和同时出现的焦虑和抑郁症诊断在RA患者中升高并增加.
- 增加的发病率表明人们对这些心理健康状况的认识和诊断增加了.
- 对于RA患者来说,精神健康诊断差距越来越大,需要临床干预.
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