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Updated: Jun 10, 2025

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain

Published on: July 12, 2012

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关于脑组织转录和DNA甲基化的一项多omics研究揭示了ADHD的遗传病原性

Jingkai Wang1, Qiu-Wen Zhu1, Jia-Hao Mai1

  • 1Department of Biostatistics, State Key Laboratory of Organ Failure Research, Ministry of Education, and Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou 510515, China.

Briefings in bioinformatics
|October 15, 2024
PubMed
概括

这项研究揭示了基因表达和DNA甲基化如何因果关系地影响14个大脑组织的注意力缺陷/多动性障碍 (ADHD). 研究结果确定了关键的基因和途径,为ADHD提供了洞察力.

关键词:
通过DNA甲基化.门德尔的随机化替代性拼接是一种替代性的拼接.注意力缺陷/多动症障碍.多种主题的多种主题.转录组广泛的关联研究研究.

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