三甘油糖相关指数是 Sarcopenia 的一个指标
Zihao Zhang1, Xin Chen2,3, Na Jiang4
1Medical College, Qingdao University, Qingdao, 266000, China. zzh990129@163.com.
Scientific reports
|October 15, 2024
概括
甘油三糖 (TyG) 指数和相关指标显示与肉症有显著的关联. 泰格-身体质量指数 (TyG-BMI) 显示出最强的预测能力,用于识别老年人肉症风险.
科学领域:
- 老年学是指老年学的学科.
- 代谢健康 代谢健康
- 流行病学 流行病学
背景情况:
- 胰岛素耐药性 (IR) 在老年人群中越来越令人担忧.
- 三甘油糖 (TyG) 指数是评估IR的新型指标.
- 泰格指数和肉症之间的关联仍未得到充分研究.
研究的目的:
- 调查TyG指数及其变体对肉症的预测潜力.
- 探讨与TyG相关的指数与老年人患皮病的风险之间的关系.
主要方法:
- 利用了来自45岁以上的10,537名中国健康与退休长度研究参与者的数据.
- 采用多变量逻辑回归,ROC曲线分析和Cox比例危险模型.
- 应用限制立方线回归 (RCS) 来分析非线性关系.
主要成果:
- TyG,TyG-身体质量指数 (TyG-BMI) 和TyG-腰围 (TyG-WC) 与肉症有显著的联系.
- 在ROC分析中,AUC值为0.659 (TyG),0.903 (TyG-BMI) 和0.819 (TyG-WC).
- 泰格-BMI表现出对萨尔科佩尼亚最强的预测能力.
结论:
- 与TyG相关的指数,特别是TyG-BMI,显示了老年人肉症的显著预测价值.
- 这些发现表明,基于TyG的指标可能有助于早期识别和治疗肉类.
- 需要进一步的研究来阐明与IR和肉症相关的潜在机制.
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