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结合左心房尾闭塞和导管切除手术用于左心房失常症:一个现实世界,倾向匹配的分析

Stefan Preisendörfer¹, Muhammad T Ayub¹, Aakash Sheth¹

¹Heart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Journal of cardiovascular electrophysiology

|October 16, 2024

概括

与单独使用LAAO相比,结合的皮左心房附属物阻塞 (LAAO) 和导管切除 (CA) 显示出相似的安全性和有效性. 这项现实研究发现,在两种手术之间,主要并发症,血栓形成和死亡率的结果相似.

科学领域:

心脏病学心脏病学
干预心脏病学干预心脏病学
电子生理学电子生理学

背景情况:

有限的现实世界数据存在,比较左心房附属物阻塞 (LAAO) 和导管切除 (CA) 与LAAO单独的结合.
评估联合手术的安全性和有效性对于优化患者护理至关重要.

研究的目的:

在一个大型的真实世界患者队列中,比较LAAO和CA联合治疗的安全性和有效性与单独的LAAO.
为了评估六个月后的医院并发症,设备相关的结果和临床事件.

主要方法:

从美国大型医院系统中,对接受LAAO和CA联合治疗的患者与单独接受LAAO的患者的回顾性分析 (8/2020-2/2024).
倾向性得分匹配 (1:2比) 用于控制基线特征,包括设备类型,CHA2DS2-VASc和HAS-BLED得分.
评估的结果包括程序成功,住院并发症,周周器件泄漏,器件血栓,所有原因死亡率,血栓塞栓事件和出血事件.

主要成果:

在两组中,LAAO植入成功率相同 (95.8%).
在医院住院的重大和轻微并发症在联合和LAAO单独组之间是相似的.
在45天和6个月后,设备周边泄漏,设备相关血栓,所有原因死亡率,血栓栓塞和出血事件在两组之间是可比的.

结论:

联合LAAO和CA是一种安全有效的策略,其结果与单独的LAAO相美.
这些发现支持在必要时使用组合程序,提供类似的安全配置文件.
进一步的前性研究可能进一步阐明长期益处和特定的患者选择标准.

关键词:

心房动是心房动的一种.导管切除导管切除导管切除导管切除联合程序联合程序左心房附属体封闭闭塞的情况肺静脉隔离肺静脉隔离肺静脉隔离

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