交叉连接器架构对动态共价气凝中的影响粘弹性产生影响.
Yung-Hao Lin1, Junzhe Lou2, Yan Xia3
1Department of Chemical Engineering, Stanford University, Stanford, CA, 94305, USA.
Advanced healthcare materials
|October 16, 2024
概括
动态共价交联 (DCC) 水凝具有可调节的机械性能. 这项研究揭示了基于酸的酸水凝中的交叉链架构如何对生物材料应用的刚性和粘性弹性产生重大影响.
科学领域:
- 生物材料科学 生物材料科学
- 聚合物化学 聚合物化学
- 机械生物学 机械生物学
背景情况:
- 动态共价交联 (DCC) 水凝模仿本地组织机制,具有粘性弹性和自我愈合.
- 传统的水凝缺乏DCC水凝的调节性机械性能.
- 交叉连接器架构对DCC水凝粘性弹性的影响仍未得到充分研究.
研究的目的:
- 研究不同交叉连接器架构如何影响基于酸的酸水凝的刚性和粘性.
- 为设计具有特定机械配置的DCC水凝建立结构-属性关系.
主要方法:
- 合成的酸水凝利用酸动态共价化学.
- 多样化的交叉连接器度,固态度和架构 (侧链交叉连接器 (SCX),线性远程连接器 (LX) 和恒星远程连接器 (SX)).
- 描述了水凝的机械性能,包括刚性和应力放松动态.
主要成果:
- SCX水凝:增加硬性和较慢的应力放松与更高的度;减少硬性和更快的放松与非静态度比.
- 望远镜式水凝 (LX和SX):在中间混合比率下最大的刚性和放松;更高的价值增强性质.
- 跨架构实现了明显的机械性质范围;SCX表现出较慢的放松,SX表现出比LX更大的刚性和较慢的放松.
结论:
- 交叉连接器架构是DCC水凝刚性和粘性弹性的关键决定因素.
- 定制交叉连接器设计允许精确控制水凝的机械性能.
- 这些发现为开发用于再生医学和机械生物学的先进DCC水凝提供了基础.
相关概念视频
01:16Dynamic Modulus of Elasticity of Concrete
267
The dynamic modulus of elasticity assesses how a concrete structure deforms under impact or dynamic loads. It is typically higher than the static modulus of elasticity, measured under slow, steady loading conditions.
The sonic test is a common method to determine the dynamic modulus. In this test, a concrete beam, sized either 6 x 6 x 30 inches or 4 x 4 x 20 inches, is clamped at its center. Vibrations are initiated at one end of the beam by an electromagnetic exciter unit powered by...
The sonic test is a common method to determine the dynamic modulus. In this test, a concrete beam, sized either 6 x 6 x 30 inches or 4 x 4 x 20 inches, is clamped at its center. Vibrations are initiated at one end of the beam by an electromagnetic exciter unit powered by...
267
01:20Elasticity in Concrete
87
Upon subjecting concrete to moderate or high uniaxial compressive or tensile stresses, the strain response is non-linear relative to the stress applied. As the stress is removed, the resulting stress-strain curve deviates from the original path traced during loading, creating a hysteresis loop, indicative of the concrete's non-linear and non-elastic properties. Typically, a material's modulus of elasticity, which is a measure of the material's stiffness, is inferred from the linear...
87
01:22Generalized Hooke's Law
853
The generalized Hooke's Law is a broadened version of Hooke's Law, which extends to all types of stress and in every direction. Consider an isotropic material shaped into a cube subjected to multiaxial loading. In this scenario, normal stresses are exerted along the three coordinate axes. As a result of these stresses, the cubic shape deforms into a rectangular parallelepiped. Despite this deformation, the new shape maintains equal sides, and there is a normal strain in the direction of the...
853