全球抗击疟疾:目标和成就 1900-2022年
Marc Thellier1,2, Ayawovi Arlene Jessicka Gemegah1, Ilhame Tantaoui1
1AP-HP, Centre National de Référence du Paludisme, Hôpital Pitié-Salpêtrière, 75013 Paris, France.
Journal of clinical medicine
|October 16, 2024
概括
消除疟疾的努力面临着巨大的挑战,尽管一个世纪的工作. 了解它的历史和演变对于制定有效的未来战略来打击这种全球健康威胁至关重要.
科学领域:
- 医学昆虫学 医学昆虫学
- 寄生虫学的寄生虫学
- 全球健康 全球健康
背景情况:
- 疟疾是由虫寄生虫引起的,并由虫蚊子传播,仍然是一个关键的全球卫生问题.
- 尽管进行了广泛的控制工作,2022年有2.49亿例病例和60万例死亡.
- 世界卫生组织的全球技术战略旨在到2030年将发病率和死亡率降低90%.
研究的目的:
- 检查历史和当前的疟疾控制和根除工作.
- 分析过去和现在战略的成功和失败.
- 强调在未来的疟疾根除计划中需要历史背景.
主要方法:
- 疟疾控制倡议的历史审查.
- 分析与疟疾有关的科学发现.
- 审查世界卫生组织的战略和进展报告.
主要成果:
- 实现2030年目标的进展有限:到2022年,仅减少2%的发病率和6%的死亡率.
- 1955年全球疟疾根除计划由于后勤问题,DDT耐药性和资金缺口而失败.
- 持续面临的挑战包括卫生系统疲软,药物/杀虫剂耐药性和资金不足.
结论:
- 消除疟疾仍然是一个遥远的目标.
- 历史的理解对于为未来的战略提供信息至关重要.
- 持续的研究和持续的资金对于进步至关重要.
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