在手术前红细胞分布宽度和在最小侵入性中枢门手术患者中长期使用catecholamines的术后使用之间的关系:回顾性队列研究
Alfonso Carrara1, Lorenzo Peluso1,2, Federica Baccanelli1
1Department of Anesthesia and Intensive Care, Humanitas Gavazzeni, Via M. Gavazzeni, 21, 24125 Bergamo, Italy.
Journal of clinical medicine
|October 16, 2024
概括
红细胞分布宽度 (RDW) 升高可能预测在最小侵入性心肌手术中需要长期使用手术后的甲醇胺. 超过14.4%的RDW与这一结果独立相关.
科学领域:
- 心脏病学 心脏病学
- 血液学 血液学 血液学
- 手术创新 在外科创新.
背景情况:
- 红细胞分布宽度 (RDW) 的升高是心脏手术中不良结果的已知预测因素.
- 它在预测外科手术期间的血液动力学不稳定性方面的作用,特别是术后长期使用甲醇胺,需要进一步研究.
研究的目的:
- 为了研究术前RDW和术后长期使用甲基荷胺 (PPUC) 之间的关联,在接受微创性心脏门手术的患者中.
主要方法:
- 对343名接受微创性米特拉手术 (机器人辅助和非机器人辅助) 的患者进行了回顾性单心队列研究.
- PPUC被定义为在ICU入院后≥12小时内使用异能剂/血管压缩剂.
- 进行了多变量逻辑回归分析,以确定PPUC的独立预测因子.
主要成果:
- 一个高的手术前RDW (>14.4%) 独立地与PPUC相关 (OR 2.62;p=0.03).
- EuroSCORE II (OR 1.38;p=0.03) 和交叉时间 (OR 1.01;p<0.01) 也独立预测了PPUC.
- 机器人辅助的 mitra 门手术与降低血动力学损伤相关 (OR 0.53; p<0.03).
结论:
- 术前 RDW >14.4%,EuroSCORE II 和交叉时间是术后在最小侵入性中长期使用甲基胺的独立预测因素.
- 机器人辅助的方法似乎与手术后更少的血液动力学妥协有关.
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