通过手术和持续正气道压力治疗阻塞性睡眠呼吸暂停的有效性:使用客观睡眠参数和患者报告结果的评估
Yu-Ching Hsu1,2,3, Jung-Der Wang1,4, Sheng-Mao Chang5
1Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.
Journal of clinical medicine
|October 16, 2024
概括
通过改善关键睡眠参数,手术干预和CPAP治疗为阻塞性睡眠呼吸暂停 (OSA) 提供了持续的长期益处. 然而,打可能会在几年后复发,影响患者参与的决策.
科学领域:
- 睡眠医学 睡眠医学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 肺部病理学 肺部病理学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种常见的疾病,可以通过手术 (UPPP,PNS) 或CPAP治疗.
- 这些OSA治疗对睡眠参数和患者结果的长期影响尚未完全理解.
研究的目的:
- 评估UPPP,PNS和CPAP对中度至重度OSA的长期疗效.
- 为了评估客观睡眠参数和患者报告的结果随时间变化的变化.
主要方法:
- 从2011年至2018年对448名中度至重度OSA患者的回顾性分析.
- 目标措施: 呼吸暂停-呼吸暂停指数 (AHI),最低O2和,睡眠效率.
- 患者报告的结果:打结果调查,爱普沃思睡眠度量表. 使用混合效应模型进行分析.
主要成果:
- 在干预后立即,UPPP,PNS和CPAP显著改善了AHI,最小O2和和白天嗜睡.
- 这些改善是长期持续的,随着时间的推移没有显著的变化率.
- 打在短期内有所改善,但在手术后3.9-5.3年和CPAP后6.2年后恢复到基线水平.
结论:
- 手术干预和CPAP疗法在OSA管理方面表现出持续的长期有效性.
- 3.9-6.2年后打的复发凸显了持续监测和以患者为中心的决策的必要性.
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