农村成年人的脆弱性和药物适用性:通过药剂师和医生的协作努力提出干预措施
Cristina García1,2,3, José M Ocaña4, Mónica Alacreu2,5
1Community Pharmacy, 02161 Albacete, Spain.
Journal of clinical medicine
|October 16, 2024
概括
老年人的虚弱与药物风险有关. 在初级保健中优化药物使用,特别是在农村地区,对于改善健康结果和减少脆弱人群的不良事件至关重要.
科学领域:
- 老年学是一门学科.
- 主要护理医学 医疗保健
- 临床药房 临床药房
背景情况:
- 脆弱性和多种药物是初级保健中的重要问题,特别是在农村环境中.
- 潜在不合适药物 (PIM) 清单和药物评价 (MR) 是管理这些疾病的关键工具.
- 农村地区的医疗保健专业人员往往是患者唯一的医疗联系人.
研究的目的:
- 调查农村人口中药物适当性和脆弱性指标之间的关联.
- 确定在脆弱的老年人中优化药疗的策略.
- 分析脆弱性,PIMs,降落风险增加药物 (FRID) 和抗胆固醇负担 (ACB) 之间的关系.
主要方法:
- 在西班牙蒂里耶斯 (Tiriez,西班牙) 的50岁以上的241名社区居民的横截面研究 (2023年).
- 使用FRAIL尺度评估脆弱性;使用2023年标准的老年人处方查工具 (STOPP) 评估PIM.
- 独立变量包括年龄,性别,药物治疗方案,跌倒史,并发症,FRID和ACB.
主要成果:
- 大约20%的人口表现出脆弱.
- 较高的FRID和ACB分数与脆弱性显著相关 (p < 0.001).
- 脆弱性在女性中更为普遍 (OR: 3.5 [1.5, 9.0]);长时间使用抗焦虑剂和抗剂是常见的PIM.
结论:
- 在初级保健中,药物优化对脆弱患者至关重要.
- 干预措施应针对个别治疗方案的正确药物剂量和组合.
- 解决FRID和ACB对于管理老年人的脆弱性至关重要.
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