高血压患者的全球纵向和周围菌株的预测值:10年随访
Marijana Tadic1, Tamara Filipovic2, Jelena Suzic1
1Department of Cardiology, University Clinical Hospital Center "Dr. Dragisa Misovic-Dedinje", 11000 Belgrade, Serbia.
Journal of clinical medicine
|October 16, 2024
概括
降低的全球纵向应变 (GLS) 和全球周边应变 (GCS) 预测高血压患者在10年内发生不良心血管事件. 这些关键的心声回声测量为不复杂的高血压提供了有价值的预后信息.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 高血压研究 高血压研究
背景情况:
- 高血压是心血管疾病的主要危险因素.
- 早期识别高血压患者的不良结果至关重要.
- 左心室 (LV) 应变分析可以提供预后见解.
研究的目的:
- 评估多向LV菌株对不良结果的预测价值.
- 评估全球纵向应变 (GLS),全球周边应变 (GCS) 和全球辐射应变 (GRS) 在没有并发症的高血压患者中.
- 确定LV菌株与主要不良心血管事件 (MACE) 的长期关联.
主要方法:
- 对591名最近被诊断为高血压患者的回顾性研究.
- 用二维斑点跟踪成像进行心声学,用于GLS,GCS和GRS测量.
- 对MACE的10年随访,包括死亡率,心肌梗塞,中风和心力衰竭.
主要成果:
- 在经历MACE的患者中观察到减少GLS,GCS和GRS.
- 减少的GLS和GCS与MACE独立相关,即使经过对临床因素和LVH进行调整.
- 减少的GRS没有显示与不良结果的独立关联.
结论:
- 降低GLS和GCS是无并发高血压患者不良结果的显著独立预测因素.
- LV 菌株参数,特别是 GLS 和 GCS,对于高血压风险分层有价值.
- 这些发现支持在管理高血压患者时使用心声波应变分析.
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